Continuous tissue glucose measurement (CGM) to drive the therapy of diabetes mellitus

Insulin pump therapy should use a flexible Teflon catheter inserted into the skin at a 30 degree angle, as these types of catheters are the least likely to injure the skin and show less inflammation of the tissue. As a result, insulin resorption becomes smoother and insulin requirements are not so different from day to day. This is also important in hybrid closed loop pump systems. The catheters must be changed every 3 days. Steel cannulas show the strongest inflammatory reaction, 90 degrees Teflon catheters have a stronger inflammatory response than 30 degrees Teflon catheters.See Study by Jeffrey I. et al .: Development of SteadiFlow Technology, Advanced Insulin Delvery Cannula Featuring Extended Duration of Use, More Reliable Insulin Delivery, and Reduced Inflammatory Tissue Response; presented at the ADA 2019 in San Francisco.